EVALUATION OF PSORIASIS PATIENTS’ ATTITUDES TOWARD BENEFIT–RISK AND THERAPEUTIC TRADE-OFFS IN THEIR CHOICE OF TREATMENTS

Evaluation of psoriasis patients’ attitudes toward benefit–risk and therapeutic trade-offs in their choice of treatments

Lina Eliasson,1 Anthony P Bewley,2 Farhan Mughal,3 Karissa M Johnston,4 Andreas Kuznik,5 Chloe Patel,1 Andrew J Lloyd1 1Clinical Outcomes Assessment, ICON Clinical Research UK Ltd, 2Department of Dermatology, Whipps Cross University Hospital, Barts Health National Health Service Trust, London, 3Health Economics Outcomes Research, Celgene Ltd, Uxbri

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Trans-ethnic meta-analysis of genome-wide association studies identifies maternal ITPR1 as a novel locus influencing fetal growth during sensitive periods in pregnancy.

Abnormal fetal growth is a risk factor for infant morbidity and mortality and is associated with cardiometabolic diseases in adults.Genetic influences on fetal growth can vary at different gestation times, but genome-wide association studies have been limited to birthweight.We performed trans-ethnic genome-wide meta-analyses and fine mapping to ide

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Enhanced Proapoptotic Effects of Water Dispersed Complexes of 4-Thiazolidinone-Based Chemotherapeutics with a PEG-Containing Polymeric Nanocarrier

Abstract Aim To study whether water formulation of the complex of 4-thiazolidinone derivatives with Skin Care Masks a PEG-containing polymeric nanocarrier enhances their pro-apoptotic action towards rat glioma C6 cells.Methods Mechanisms of antineoplastic effects of 4-thiazolidinone derivatives were investigated in vitro with rat glioma C6 cells.Ce

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Economics of Harmful Invasive Species: A Review

The purpose of this study is to review theoretical and empirical findings in economics with respect to the challenging question of how to manage invasive species.The review revealed a relatively large body of literature on the assessment of damage costs of invasive species; single species and groups of species at different geographical scales.Howev

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A Tightly Coupled RTK/INS Algorithm with Ambiguity Resolution in the Position Domain for Ground Vehicles in Harsh Urban Environments

Vehicles driving in urban canyons are always confronted with a degraded Global Navigation Satellite System (GNSS) signal environment.The surrounding obstacles may cause signal reflections or blockages, which lead to large multipath noises and intermittent GNSS reception.Under these circumstances, it is not feasible to use conventional real-time kin

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